Regulation of immunoglobulin (Ig)E synthesis in the hyper-IgE syndrome.

The hyper-IgE (HIE) syndrome is characterized by high IgE serum levels, chronic dermatitis, and recurrent infections. The mechanisms responsible for hyperproduction of IgE in HIE patients are presently unknown. We investigated whether spontaneous in vitro IgE synthesis by PBMC from seven HIE patient...

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Publié dans:	J Clin Invest
Auteurs principaux:	Vercelli, D, Jabara, H H, Cunningham-Rundles, C, Abrams, J S, Lewis, D B, Meyer, J, Schneider, L C, Leung, D Y, Geha, R S
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Clinical Investigation 1990
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296619/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2110192/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114618
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