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Identification of a Novel HSP70-binding Cochaperone Critical to HSP90-mediated Activation of Small Serine/Threonine Kinase

We previously reported the identification of small serine/threonine kinase (SSTK) that is expressed in postmeiotic germ cells, associates with HSP90, and is indispensable for male fertility. Sperm from SSTK-null mice cannot fertilize eggs in vitro and are incapable of fusing with eggs that lack zona...

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Detalhes bibliográficos
Main Authors: Jha, Kula N., Wong, Lily, Zerfas, Patricia M., De Silva, Rukman S., Fan, Ying-Xin, Spiridonov, Nikolay A., Johnson, Gibbes R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966131/
https://ncbi.nlm.nih.gov/pubmed/20829357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.134767
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