C/EBPδ and STAT-1 Are Required for TLR8 Transcriptional Activity

Toll-like receptor 8 (TLR8), which is expressed primarily in myeloid cells, plays a central role in initiating immune responses to viral single-stranded RNA. Despite the great interest in the field of TLR8 research, very little is known in terms of TLR8 biology and its transcriptional regulation. He...

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Dettagli Bibliografici
Autori principali: Zannetti, Claudia, Bonnay, François, Takeshita, Fumihiko, Parroche, Peggy, Ménétrier-Caux, Christine, Tommasino, Massimo, Hasan, Uzma A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2010
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966093/
https://ncbi.nlm.nih.gov/pubmed/20829351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.133884
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