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Lipidation by the Host Prenyltransferase Machinery Facilitates Membrane Localization of Legionella pneumophila Effector Proteins

The intracellular human pathogen Legionella pneumophila translocates multiple proteins in the host cytosol known as effectors, which subvert host cellular processes to create a membrane-bound organelle that supports bacterial replication. It was observed that several Legionella effectors encode a pr...

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Autors principals: Ivanov, Stanimir S., Charron, Guillaume, Hang, Howard C., Roy, Craig R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966084/
https://ncbi.nlm.nih.gov/pubmed/20813839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.170746
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