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Exploitation of conserved eukaryotic host cell farnesylation machinery by an F-box effector of Legionella pneumophila
Farnesylation involves covalent linkage of eukaryotic proteins to a lipid moiety to anchor them into membranes, which is essential for the biological function of Ras and other proteins. A large cadre of bacterial effectors is injected into host cells by intravacuolar pathogens through elaborate type...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
The Rockefeller University Press
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2916131/ https://ncbi.nlm.nih.gov/pubmed/20660614 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20100771 |
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