Expanding Role of the Jumonji C Domain as an RNA Hydroxylase

JmjC (Jumonji C) domain-containing proteins are known to be an extensive family of Fe(II)/2-oxoglutarate-dependent oxygenases involved in epigenetic regulation of gene expression by catalyzing oxidative demethylation of methylated histones. We report here that a human JmjC protein named Tyw5p (TYW5)...

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Bibliografiske detaljer
Main Authors: Noma, Akiko, Ishitani, Ryuichiro, Kato, Megumi, Nagao, Asuteka, Nureki, Osamu, Suzuki, Tsutomu
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2010
Fag:
RNA
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966065/
https://ncbi.nlm.nih.gov/pubmed/20739293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.156398
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