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Structural basis of AdoMet-dependent aminocarboxypropyl transfer reaction catalyzed by tRNA-wybutosine synthesizing enzyme, TYW2

S-adenosylmethionine (AdoMet) is a methyl donor used by a wide variety of methyltransferases, and it is also used as the source of an α-amino-α-carboxypropyl (“acp”) group by several enzymes. tRNA-yW synthesizing enzyme-2 (TYW2) is involved in the biogenesis of a hypermodified nucleotide, wybutosine...

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Detalhes bibliográficos
Main Authors: Umitsu, Masataka, Nishimasu, Hiroshi, Noma, Akiko, Suzuki, Tsutomu, Ishitani, Ryuichiro, Nureki, Osamu
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747168/
https://ncbi.nlm.nih.gov/pubmed/19717466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0905270106
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