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Identification of a Novel Transport-independent Function of PiT1/SLC20A1 in the Regulation of TNF-induced Apoptosis

PiT1/SLC20A1 is a sodium-dependent P(i) transporter expressed by most mammalian cells. Interestingly, PiT1 transcription has been shown to be up-regulated by the tumor necrosis factor α (TNF), and we have now investigated the possible involvement of PiT1 in TNF-induced apoptosis. We show that PiT1-d...

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主要な著者: Salaün, Christine, Leroy, Christine, Rousseau, Alice, Boitez, Valérie, Beck, Laurent, Friedlander, Gérard
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2010
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966055/
https://ncbi.nlm.nih.gov/pubmed/20817733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.130989
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