Effects of GsMTx4 on Bacterial Mechanosensitive Channels in Inside-Out Patches from Giant Spheroplasts

GsMTx4 is a 34-residue peptide isolated from the tarantula Grammostola spatulata folded into an inhibitory cysteine knot and it selectively affects gating of some mechanosensitive channels. Here we report the effects of cytoplasmic GsMTx4 on the two bacterial channels, MscS and MscL, in giant Escher...

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Hauptverfasser: Kamaraju, Kishore, Gottlieb, Philip A., Sachs, Frederick, Sukharev, Sergei
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2010
Schlagworte:
Channels and Transporters
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965992/
https://ncbi.nlm.nih.gov/pubmed/21044584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.09.022
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