Effects of GsMTx4 on Bacterial Mechanosensitive Channels in Inside-Out Patches from Giant Spheroplasts

GsMTx4 is a 34-residue peptide isolated from the tarantula Grammostola spatulata folded into an inhibitory cysteine knot and it selectively affects gating of some mechanosensitive channels. Here we report the effects of cytoplasmic GsMTx4 on the two bacterial channels, MscS and MscL, in giant Escher...

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Bibliographic Details
Main Authors: Kamaraju, Kishore, Gottlieb, Philip A., Sachs, Frederick, Sukharev, Sergei
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2010
Subjects:
Channels and Transporters
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965992/
https://ncbi.nlm.nih.gov/pubmed/21044584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.09.022
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