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Modeling the Effect of Kv1.5 Block on the Canine Action Potential

A wide range of ion channels have been considered as potential targets for pharmacological treatment of atrial fibrillation. The Kv1.5 channel, carrying the I(Kur) current, has received special attention because it contributes to repolarization in the atria but is absent or weakly expressed in ventr...

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Autori principali: Almquist, Joachim, Wallman, Mikael, Jacobson, Ingemar, Jirstrand, Mats
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965949/
https://ncbi.nlm.nih.gov/pubmed/21044569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.08.062
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