Loading...
c-Cbl acts as a mediator of Src-induced activation of the PI3K-Akt signal transduction pathway during TRAIL treatment
We have previously observed that TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) induces acquired TRAIL resistance by increasing Akt phosphorylation and Bcl-xL expression. In this study, we report that Src, c-Cbl, and PI3K are involved in the phosphorylation of Akt during TRAIL treat...
Na minha lista:
| Main Authors: | , , , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2965849/ https://ncbi.nlm.nih.gov/pubmed/19861161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2009.10.007 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|