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Microarray analysis of hippocampal CA1 neurons implicates early endosomal dysfunction during Alzheimer’s disease progression

BACKGROUND: Endocytic dysfunction and neurotrophin signaling deficits may underlie the selective vulnerability of hippocampal neurons during the progression of Alzheimer’s disease (AD), although there is little direct in vivo and biochemical evidence to support this hypothesis. METHODS: Microarray a...

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Detalhes bibliográficos
Main Authors: Ginsberg, Stephen D., Alldred, Melissa J., Counts, Scott E., Cataldo, Anne M., Neve, Rachael L., Jiang, Ying, Wuu, Joanne, Chao, Moses V., Mufson, Elliott J., Nixon, Ralph A., Che, Shaoli
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965820/
https://ncbi.nlm.nih.gov/pubmed/20655510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2010.05.030
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