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Surveys of Non-Ribosomal Peptide and Polyketide Assembly Lines in Fungi and Prospects for Their Analysis in vitro and in vivo

With many bioactive non-ribosomal peptides and polyketides produced in fungi, studies of their biosyntheses are an active area of research. Practical limitations of working with mega-dalton synthetases including cell lysis and protein extraction to recombinant gene and pathway expression has slowed...

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Detalhes bibliográficos
Main Authors: Evans, Bradley S., Robinson, Sarah J., Kelleher, Neil L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965788/
https://ncbi.nlm.nih.gov/pubmed/20601041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fgb.2010.06.012
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