What Is Vinculin Needed for in Platelets?

BACKGROUND: Vinculin links integrins to the cell cytoskeleton by virtue of its binding to proteins such as talin and F-actin. It has been implicated in the transmission of mechanical forces from the extracellular matrix to the cytoskeleton of migrating cells. Vinculin’s function in platelets is unkn...

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Bibliografiske detaljer
Main Authors: Mitsios, John V., Prévost, Nicolas, Kasirer-Friede, Ana, Gutierrez, Edgar, Groisman, Alex, Abrams, Charles S., Wang, Yanfeng, Litvinov, Rustem I., Zemljic-Harpf, Alice, Ross, Robert S., Shattil, Sanford J.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965783/
https://ncbi.nlm.nih.gov/pubmed/20670372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1538-7836.2010.03998.x
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