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Altering a Histone H3K4 Methylation Pathway in Glomerular Podocytes Promotes a Chronic Disease Phenotype

Methylation of specific lysine residues in core histone proteins is essential for embryonic development and can impart active and inactive epigenetic marks on chromatin domains. The ubiquitous nuclear protein PTIP is encoded by the Paxip1 gene and is an essential component of a histone H3 lysine 4 (...

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Detalhes bibliográficos
Main Authors: Lefevre, Gaelle M., Patel, Sanjeevkumar R., Kim, Doyeob, Tessarollo, Lino, Dressler, Gregory R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965754/
https://ncbi.nlm.nih.gov/pubmed/21060806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001142
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