Ex-vivo expanded human NK cells express activating receptors that mediate cytotoxicity of allogeneic and autologous cancer cell lines by direct recognition and antibody directed cellular cytotoxicity

BACKGROUND: The possibility that autologous NK cells could serve as an effective treatment modality for solid tumors has long been considered. However, implementation is hampered by (i) the small number of NK cells in peripheral blood, (ii) the difficulties associated with large-scale production of...

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Bibliografski detalji
Glavni autori: Voskens, Caroline J, Watanabe, Ryuko, Rollins, Sandra, Campana, Dario, Hasumi, Kenichiro, Mann, Dean L
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2010
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965714/
https://ncbi.nlm.nih.gov/pubmed/20937115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-29-134
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