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Feedback regulation of bile-acid synthesis in the rat. Differing effects of taurocholate and tauroursocholate.

We studied the effect of the orientation of the 7-hydroxyl group in taurocholate (7 alpha) and tauroursocholate (7 beta) on the feedback regulation of bile-acid synthesis and its rate-controlling enzyme, cholesterol 7 alpha-hydroxylase, in bile-fistula rats. To ensure a constant supply of cholestero...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Principais autores: Shefer, S, Nguyen, L, Salen, G, Batta, A K, Brooker, D, Zaki, F G, Rani, I, Tint, G S
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 1990
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296551/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2318973/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114552
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