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Feedback regulation of bile-acid synthesis in the rat. Differing effects of taurocholate and tauroursocholate.

We studied the effect of the orientation of the 7-hydroxyl group in taurocholate (7 alpha) and tauroursocholate (7 beta) on the feedback regulation of bile-acid synthesis and its rate-controlling enzyme, cholesterol 7 alpha-hydroxylase, in bile-fistula rats. To ensure a constant supply of cholestero...

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Bibliografiske detaljer
Main Authors: Shefer, S, Nguyen, L, Salen, G, Batta, A K, Brooker, D, Zaki, F G, Rani, I, Tint, G S
Format: Artigo
Sprog:Inglês
Udgivet: 1990
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC296551/
https://ncbi.nlm.nih.gov/pubmed/2318973
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