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SHIP2, a factor associated with diet-induced obesity and insulin sensitivity, attenuates FGF signaling in vivo

SH2-domain-containing inositol phosphatase 2 (SHIP2) belongs to a small family of phosphoinositide 5-phosphatases that help terminate intracellular signaling initiated by activated receptor tyrosine kinases. Mammalian SHIP2 is viewed primarily as an attenuator of insulin signaling and has become a p...

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Detalhes bibliográficos
Main Authors: Jurynec, Michael J., Grunwald, David Jonah
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Limited 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965400/
https://ncbi.nlm.nih.gov/pubmed/20616095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.000703
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