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Disease-associated human histocompatibility leukocyte antigen determinants in patients with seropositive rheumatoid arthritis. Functional role in antigen-specific and allogeneic T cell recognition.

The susceptibility to develop seropositive rheumatoid arthritis (RA) has been linked to specific genomic polymorphisms within the HLA complex. Two different haplotypes have been associated with the disease, HLA-DR1 and HLA-DR4. To investigate the link between such phenotypic disease associations and...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Weyand, C M, Goronzy, J J
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296534/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1690755/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114535
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