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Inhibition of KIT RNAi mediated with adenovirus in gastrointestinal stromal tumor xenograft

AIM: To investigate a therapeutic method for gastrointestinal stromal tumor (GIST) based on KIT RNA interference (RNAi) with AdMax adenovirus. METHODS: KIT short hairpin RNA (shRNA), whose lateral sides were decorated with restriction endonuclease sequences, was designed. T(4) DNA ligase catalyzed t...

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Huvudupphovsmän: Wang, Tian-Bao, Huang, Wen-Sheng, Lin, Wei-Hao, Shi, Han-Ping, Dong, Wen-Guang
Materialtyp: Artigo
Språk:Inglês
Publicerad: Baishideng Publishing Group Co., Limited 2010
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965291/
https://ncbi.nlm.nih.gov/pubmed/20976851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v16.i40.5122
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