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Reliable semi-synthesis of hydrolysis-resistant 3′-peptidyl-tRNA conjugates containing genuine tRNA modifications

The 3′-peptidyl-tRNA conjugates that possess a hydrolysis-resistant ribose-3′-amide linkage instead of the natural ester linkage would represent valuable substrates for ribosomal studies. Up to date, access to these derivatives is severely limited. Here, we present a novel approach for the reliable...

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Autors principals: Graber, Dagmar, Moroder, Holger, Steger, Jessica, Trappl, Krista, Polacek, Norbert, Micura, Ronald
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965236/
https://ncbi.nlm.nih.gov/pubmed/20525967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq508
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