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An intact ribose moiety at A2602 of 23S rRNA is key to trigger peptidyl-tRNA hydrolysis during translation termination

Peptide bond formation and peptidyl-tRNA hydrolysis are the two elementary chemical reactions of protein synthesis catalyzed by the ribosomal peptidyl transferase ribozyme. Due to the combined effort of structural and biochemical studies, details of the peptidyl transfer reaction have become increas...

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Bibliografiske detaljer
Main Authors: Amort, Melanie, Wotzel, Brigitte, Bakowska-Zywicka, Kamilla, Erlacher, Matthias D., Micura, Ronald, Polacek, Norbert
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2007
Fag:
RNA
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1976462/
https://ncbi.nlm.nih.gov/pubmed/17660192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm539
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