A carregar...
Restoration of catalytic functions in Cre recombinase mutants by electrostatic compensation between active site and DNA substrate
Two conserved catalytic arginines, Arg-173 and Arg-292, of the tyrosine site-specific recombinase Cre are essential for the transesterification steps of strand cleavage and joining in native DNA substrates containing scissile phosphate groups. The active site tyrosine (Tyr-324) provides the nucleoph...
Na minha lista:
| Main Authors: | , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2010
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2965224/ https://ncbi.nlm.nih.gov/pubmed/20511594 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq466 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|