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Beyond the closed suture in Apert syndrome mouse models: evidence of primary effects of FGFR2 signaling on facial shape at birth
Apert syndrome is a congenital disorder caused mainly by two neighboring mutations on fibroblast growth factor receptor 2 (FGFR2). Premature closure of the coronal suture is commonly considered the identifying and primary defect triggering or preceding the additional cranial malformations of Apert p...
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Main Authors: | , , , , , , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
2010
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2965208/ https://ncbi.nlm.nih.gov/pubmed/20842696 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.22414 |
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