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Beyond the closed suture in Apert syndrome mouse models: evidence of primary effects of FGFR2 signaling on facial shape at birth

Apert syndrome is a congenital disorder caused mainly by two neighboring mutations on fibroblast growth factor receptor 2 (FGFR2). Premature closure of the coronal suture is commonly considered the identifying and primary defect triggering or preceding the additional cranial malformations of Apert p...

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Bibliografiske detaljer
Main Authors: Martínez-Abadías, Neus, Percival, Christopher, Aldridge, Kristina, Hill, Cheryl A, Ryan, Timothy, Sirivunnabood, Satama, Wang, Yingli, Jabs, Ethylin Wang, Richtsmeier, Joan T
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965208/
https://ncbi.nlm.nih.gov/pubmed/20842696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.22414
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