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Activation of p38 MAPK pathway in the skull abnormalities of Apert syndrome Fgfr2(+P253R )mice
BACKGROUND: Apert syndrome is characterized by craniosynostosis and limb abnormalities and is primarily caused by FGFR2 +/P253R and +/S252W mutations. The former mutation is present in approximately one third whereas the latter mutation is present in two-thirds of the patients with this condition. W...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2838826/ https://ncbi.nlm.nih.gov/pubmed/20175913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-213X-10-22 |
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