Dimethylthiourea protects against chlorine induced changes in airway function in a murine model of irritant induced asthma

BACKGROUND: Exposure to chlorine (Cl(2)) causes airway injury, characterized by oxidative damage, an influx of inflammatory cells and airway hyperresponsiveness. We hypothesized that Cl(2)-induced airway injury may be attenuated by antioxidant treatment, even after the initial injury. METHODS: Balb/...

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Detalhes bibliográficos
Main Authors: McGovern, Toby K, Powell, William S, Day, Brian J, White, Carl W, Govindaraju, Karuthapillai, Karmouty-Quintana, Harry, Lavoie, Normand, Tan, Ju Jing, Martin, James G
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965137/
https://ncbi.nlm.nih.gov/pubmed/20925946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-11-138
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