Heterogeneity of Breast Cancer Metastases: Comparison of Therapeutic Target Expression and Promoter Methylation Between Primary Tumors and Their Multifocal Metastases

PURPOSE: A comprehensive comparison of biomarker expression between patients' primary breast carcinoma (PBC) and their metastatic breast carcinomas (MBC) has not been done. EXPERIMENTAL DESIGN: We did rapid autopsies (postmortem intervals, 1-4 hours) on 10 consenting patients who died of MBC. W...

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Bibliografiske detaljer
Main Authors: Wu, Julie M., Fackler, Mary Jo, Halushka, Marc K., Molavi, Diana W., Taylor, M. Evangeline, Teo, Wei Wen, Griffin, Constance, Fetting, John, Davidson, Nancy E., De Marzo, Angelo M., Hicks, Jessica L., Chitale, Dhananjay, Ladanyi, Marc, Sukumar, Saraswati, Argani, Pedram
Format: Artigo
Sprog:Inglês
Udgivet: 2008
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965068/
https://ncbi.nlm.nih.gov/pubmed/18381931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-07-4082
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