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Combining an Internal Pilot with an Interim Analysis for Single Degree of Freedom Tests

An internal pilot with interim analysis (IPIA) design combines interim power analysis (an internal pilot) with interim data analysis (two stage group sequential). We provide IPIA methods for single df hypotheses within the Gaussian general linear model, including one and two group t tests. The desig...

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Autori principali: Kairalla, John A., Muller, Keith E., Coffey, Christopher S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965034/
https://ncbi.nlm.nih.gov/pubmed/21037942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/03610920903353709
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