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Molecular profiling of cytomegalovirus-induced human CD8(+) T cell differentiation

CD8(+) T cells play a critical role in the immune response to viral pathogens. Persistent human cytomegalovirus (HCMV) infection results in a strong increase in the number of virus-specific, quiescent effector-type CD8(+) T cells with constitutive cytolytic activity, but the molecular pathways invol...

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Détails bibliographiques
Auteurs principaux: Hertoghs, Kirsten M.L., Moerland, Perry D., van Stijn, Amber, Remmerswaal, Ester B.M., Yong, Sila L., van de Berg, Pablo J.E.J., van Ham, S. Marieke, Baas, Frank, ten Berge, Ineke J.M., van Lier, René A.W.
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964975/
https://ncbi.nlm.nih.gov/pubmed/20921622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI42758
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