Molecular profiling of cytomegalovirus-induced human CD8(+) T cell differentiation

CD8(+) T cells play a critical role in the immune response to viral pathogens. Persistent human cytomegalovirus (HCMV) infection results in a strong increase in the number of virus-specific, quiescent effector-type CD8(+) T cells with constitutive cytolytic activity, but the molecular pathways invol...

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Autors principals: Hertoghs, Kirsten M.L., Moerland, Perry D., van Stijn, Amber, Remmerswaal, Ester B.M., Yong, Sila L., van de Berg, Pablo J.E.J., van Ham, S. Marieke, Baas, Frank, ten Berge, Ineke J.M., van Lier, René A.W.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2010
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964975/
https://ncbi.nlm.nih.gov/pubmed/20921622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI42758
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