Distinct growth hormone receptor signaling modes regulate skeletal muscle development and insulin sensitivity in mice

Skeletal muscle development, nutrient uptake, and nutrient utilization is largely coordinated by growth hormone (GH) and its downstream effectors, in particular, IGF-1. However, it is not clear which effects of GH on skeletal muscle are direct and which are secondary to GH-induced IGF-1 expression....

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Detalhes bibliográficos
Main Authors: Mavalli, Mahendra D., DiGirolamo, Douglas J., Fan, Yong, Riddle, Ryan C., Campbell, Kenneth S., van Groen, Thomas, Frank, Stuart J., Sperling, Mark A., Esser, Karyn A., Bamman, Marcas M., Clemens, Thomas L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964973/
https://ncbi.nlm.nih.gov/pubmed/20921627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI42447
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