Transfection of cells from patients with leukocyte adhesion deficiency with an integrin beta subunit (CD18) restores lymphocyte function-associated antigen-1 expression and function.
Leukocyte adhesion deficiency (LAD) is an inherited immunodeficiency disease that is characterized by the deficient expression of the leukocyte adhesion glycoproteins lymphocyte function-associated antigen-1 (LFA-1), Mac-1, and p150,95. This loss of expression is attributed to heterogeneous defects...
Enregistré dans:
| Publié dans: | J Clin Invest |
|---|---|
| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Clinical Investigation
1990
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296482/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1968909/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114491 |
| Tags: |
Pas de tags, Soyez le premier à ajouter un tag!
|