Transfection of cells from patients with leukocyte adhesion deficiency with an integrin beta subunit (CD18) restores lymphocyte function-associated antigen-1 expression and function.

Leukocyte adhesion deficiency (LAD) is an inherited immunodeficiency disease that is characterized by the deficient expression of the leukocyte adhesion glycoproteins lymphocyte function-associated antigen-1 (LFA-1), Mac-1, and p150,95. This loss of expression is attributed to heterogeneous defects...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Hibbs, M L, Wardlaw, A J, Stacker, S A, Anderson, D C, Lee, A, Roberts, T M, Springer, T A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296482/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1968909/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114491
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