Preparation, Characterization and in vivo Evaluation of Parenteral Sustained Release Microsphere Formulation of Zopiclone
The aim of this study was to prepare zopiclone-loaded polycaprolactone microspheres by emulsion solvent evaporation technique with different drug-to-carrier ratios {MP 1 (1:1), MP 2 (1:2), MP 3 (1:3), and MP 4 (1:4)}, characterize and evaluate the in vivo performance. The microspheres were character...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Medknow Publications
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2964772/ https://ncbi.nlm.nih.gov/pubmed/21042475 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0975-1483.66792 |
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