Oxygen-derived free radicals stimulate osteoclastic bone resorption in rodent bone in vitro and in vivo.

The mechanisms by which bone resorbing osteoclasts form and are activated by hormones are poorly understood. We show here that the generation of oxygen-derived free radicals in cultured bone is associated with the formation of new osteoclasts and enhanced bone resorption, identical to the effects se...

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Опубликовано в::	J Clin Invest
Главные авторы:	Garrett, I R, Boyce, B F, Oreffo, R O, Bonewald, L, Poser, J, Mundy, G R
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Clinical Investigation 1990
Предметы:	Research Article
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296476/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2312718/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114485
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