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Dok-7 regulates neuromuscular synapse formation by recruiting Crk and Crk-L
Agrin, released by motor neurons, promotes neuromuscular synapse formation by stimulating MuSK, a receptor tyrosine kinase expressed in skeletal muscle. Phosphorylated MuSK recruits docking protein-7 (Dok-7), an adaptor protein that is expressed selectively in muscle. In the absence of Dok-7, neurom...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Cold Spring Harbor Laboratory Press
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2964755/ https://ncbi.nlm.nih.gov/pubmed/21041412 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1977710 |
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