Dok-7 regulates neuromuscular synapse formation by recruiting Crk and Crk-L

Agrin, released by motor neurons, promotes neuromuscular synapse formation by stimulating MuSK, a receptor tyrosine kinase expressed in skeletal muscle. Phosphorylated MuSK recruits docking protein-7 (Dok-7), an adaptor protein that is expressed selectively in muscle. In the absence of Dok-7, neurom...

Full description

Saved in:
Bibliographic Details
Main Authors: Hallock, Peter T., Xu, Chong-Feng, Park, Tae-Ju, Neubert, Thomas A., Curran, Tom, Burden, Steven J.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2010
Subjects:
Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964755/
https://ncbi.nlm.nih.gov/pubmed/21041412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1977710
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items