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Impact of ozone exposure on the phagocytic activity of human surfactant protein A (SP-A) and SP-A variants
Surfactant protein A (SP-A) enhances phagocytosis of Pseudomonas aeruginosa. SP-A1 and SP-A2 encode human (h) SP-A; SP-A2 products enhance phagocytosis more than SP-A1. Oxidation can affect SP-A function. We hypothesized that in vivo and in vitro ozone-induced oxidation of SP-A (as assessed by its c...
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Autori principali: | , , , , , , , |
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Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
2007
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2964667/ https://ncbi.nlm.nih.gov/pubmed/17981957 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00288.2007 |
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