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Marked potentiation of cell swelling by cytokines in ammonia-sensitized cultured astrocytes

BACKGROUND: Brain edema leading to high intracranial pressure is a lethal complication of acute liver failure (ALF), which is believed to be cytotoxic due to swelling of astrocytes. In addition to the traditional view that elevated levels of blood and brain ammonia are involved in the mechanism of b...

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Autori principali: Rama Rao, Kakulavarapu V, Jayakumar, Arumugam R, Tong, Xiaoying, Alvarez, Veronica M, Norenberg, Michael D
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964656/
https://ncbi.nlm.nih.gov/pubmed/20942959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-7-66
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