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FasL and FADD delivery by a glioma-specific and cell cycle-dependent HSV-1 amplicon virus enhanced apoptosis in primary human brain tumors

BACKGROUND: Glioblastoma multiforme is the most malignant cancer of the brain and is notoriously difficult to treat due to the highly proliferative and infiltrative nature of the cells. Herein, we explored the combination treatment of pre-established human glioma xenograft using multiple therapeutic...

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Detalhes bibliográficos
Main Authors: Ho, Ivy A, Ng, Wai H, Lam, Paula Y
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964619/
https://ncbi.nlm.nih.gov/pubmed/20942909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-270
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