Mutations that permit residual CFTR function delay acquisition of multiple respiratory pathogens in CF patients

BACKGROUND: Lung infection by various organisms is a characteristic feature of cystic fibrosis (CF). CFTR genotype effects acquisition of Pseudomonas aeruginosa (Pa), however the effect on acquisition of other infectious organisms that frequently precede Pa is relatively unknown. Understanding the r...

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Detalhes bibliográficos
Main Authors: Green, Deanna M, McDougal, Kathryn E, Blackman, Scott M, Sosnay, Patrick R, Henderson, Lindsay B, Naughton, Kathleen M, Collaco, J Michael, Cutting, Garry R
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964615/
https://ncbi.nlm.nih.gov/pubmed/20932301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-11-140
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