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A critical role for regulatory T cell–mediated control of inflammation in the absence of commensal microbiota

Suppression mediated by regulatory T cells (T reg cells) represents a unique, cell-extrinsic mechanism of in-trans negative regulation that restrains multiple types of immune cells. The loss of T reg cells leads to fatal, highly aggressive, and widespread immune-mediated lesions. This severe autoimm...

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Sonraí Bibleagrafaíochta
Main Authors: Chinen, Takatoshi, Volchkov, Pavel Y., Chervonsky, Alexander V., Rudensky, Alexander Y.
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Rockefeller University Press 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964571/
https://ncbi.nlm.nih.gov/pubmed/20921284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20101235
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