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Robust tests for matched case-control genetic association studies

BACKGROUND: The Cochran-Armitage trend test (CATT) is powerful in detecting association between a susceptible marker and a disease. This test, however, may suffer from a substantial loss of power when the underlying genetic model is unknown and incorrectly specified. Thus, it is useful to derive tes...

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Detalhes bibliográficos
Main Authors: Zang, Yong, Fung, Wing Kam
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964553/
https://ncbi.nlm.nih.gov/pubmed/20937159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-11-91
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