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Inhibition of Osteoclastogenesis by Mechanically Loaded Osteocytes: Involvement of MEPE

In regions of high bone loading, the mechanoresponsive osteocytes inhibit osteoclastic bone resorption by producing signaling molecules. One possible candidate is matrix extracellular phosphoglycoprotein (MEPE) because acidic serine- and aspartate-rich MEPE-associated motif peptides upregulate osteo...

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書誌詳細
主要な著者: Kulkarni, Rishikesh N., Bakker, Astrid D., Everts, Vincent, Klein-Nulend, Jenneke
フォーマット: Artigo
言語:Inglês
出版事項: Springer-Verlag 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964475/
https://ncbi.nlm.nih.gov/pubmed/20725825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00223-010-9407-7
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