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Inhibition of Osteoclastogenesis by Mechanically Loaded Osteocytes: Involvement of MEPE
In regions of high bone loading, the mechanoresponsive osteocytes inhibit osteoclastic bone resorption by producing signaling molecules. One possible candidate is matrix extracellular phosphoglycoprotein (MEPE) because acidic serine- and aspartate-rich MEPE-associated motif peptides upregulate osteo...
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| Huvudupphovsmän: | , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Springer-Verlag
2010
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2964475/ https://ncbi.nlm.nih.gov/pubmed/20725825 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00223-010-9407-7 |
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