In situ hybridization evidence for angiotensinogen messenger RNA in the rat proximal tubule. An hypothesis for the intrarenal renin angiotensin system.

We examined angiotensinogen gene expression in rat kidney by in situ hybridization histochemistry. Using a rat cRNA probe to angiotensinogen, we demonstrated angiotensinogen mRNA to be localized predominantly in the proximal renal tubule, with considerably lesser amounts in distal tubular segments a...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Ingelfinger, J R, Zuo, W M, Fon, E A, Ellison, K E, Dzau, V J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296440/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2298917/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114454
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