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In situ hybridization evidence for angiotensinogen messenger RNA in the rat proximal tubule. An hypothesis for the intrarenal renin angiotensin system.

We examined angiotensinogen gene expression in rat kidney by in situ hybridization histochemistry. Using a rat cRNA probe to angiotensinogen, we demonstrated angiotensinogen mRNA to be localized predominantly in the proximal renal tubule, with considerably lesser amounts in distal tubular segments a...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Ingelfinger, J R, Zuo, W M, Fon, E A, Ellison, K E, Dzau, V J
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1990
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296440/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2298917/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114454
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