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A Protein Inventory of Human Ribosome Biogenesis Reveals an Essential Function of Exportin 5 in 60S Subunit Export

The assembly of ribosomal subunits in eukaryotes is a complex, multistep process so far mostly studied in yeast. In S. cerevisiae, more than 200 factors including ribosomal proteins and trans-acting factors are required for the ordered assembly of 40S and 60S ribosomal subunits. To date, only few hu...

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Autori principali: Wild, Thomas, Horvath, Peter, Wyler, Emanuel, Widmann, Barbara, Badertscher, Lukas, Zemp, Ivo, Kozak, Karol, Csucs, Gabor, Lund, Elsebet, Kutay, Ulrike
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964341/
https://ncbi.nlm.nih.gov/pubmed/21048991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000522
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